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![]() ![]() Patented Schwank ceramic plate for clean combustion of the gas-air mixture.Extremely quiet operation through optimised flow condition within the burner.Forced draft fan for increasing the service life.Long, laminar flame for better heat distribution over the entire device length.This saves resources and reduces operating costs of radiant tube heating systems. The fully modulating burner enables an adjustment according to the actual heat requirement. With approximately 46 dB at a distance of 3 m, only a whisper of the burner is audible. Owing to the optimisation of the flow behaviour and the use of the pushing fan, the Whisper-Jet is an exceptionally quiet burner. This flows axially through the radiant tube and distributes the heat uniformly. Thanks to diverse simulations and the use of a patented Schwank ceramic plate, the Whisper-Jet burner ensures an extremely long and laminar flame. Furthermore, components such as the fan are kept away from hot exhaust gases, which increases the life time of the product. For instance, a pushing fan is used with the advantage that the flow characteristics of the gas-air mixture can be influenced in a better manner to ensure better heat distribution. Approved technologies and knowledge have been incorporated and implemented in its conception. Its design is a result of decades of experience in dealing with gas infrared heaters and continuous advancements. The Whisper-Jet burner is used in all product groups apart from our recently introduced deltaSchwank solution. As compared to conventional systems, savings from using radiant heating generally amount to between 30%-50%. This reduces energy costs significantly and improves the people’s sensation of warmth. This results in a balanced micro-climate made up of air and radiation heat. The surfaces absorb the thermal energy and, in turn, re-emit it into the environment. With infrared gas radiant heaters, heating therefore takes place where it is required. The infrared rays are converted into heat at the points where they fall. The Schwank infrared heaters use the same natural technology to heat buildings in an energy-efficient manner. The principle of infrared heating has been adopted from nature, because the heat rays of the sun travel through the air without heating it and emit their energy – in other words, heat – only when they fall on surfaces. The flexibility of radiant heating can therefore have a significant cost reduction benefit. For instance, separate temperature zones can be created for work stations and employee areas in warehouses while other parts of the building remain unheated. This tube heats up to approximately 580 ☌ and subsequently emits the infrared radiation.ĭecentralised radiant heating systems offer a high degree of flexibility as well as energy efficiency. In the case of tube heaters, the combustion of the gas-air mixture takes place within a long steel tube. Although a tube heater, as a decentralised infrared heating solution, uses the same physical principles as a luminous (or plaque) gas radiant heater, its functioning principle is different. ![]() ![]() These cookies are likely to be performance cookies or targeting cookies (as described below). Please note that third parties (including, for example, advertising networks and providers of external services like website analysis services) may also use cookies, over which we have no control, although we may receive services from these third parties (including, for example, for targeted advertising purposes and website analytics). 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(Some cookies are necessary in order for our website to work properly.) ![]() This page explains the cookies we use and what we use them for, and lets you turn them on or off. ![]() Cookies are small text files that are stored on your computer or other device by websites that you visit. Plumbing Superstore uses cookies on this website. ![]() ![]() Multiplayer: Continue your Halo adventure with 7 remastered multiplayer maps from Halo 2: Anniversary and 25 multiplayer maps from the original Halo 2, featuring a completely updated progression system.In the Anniversary edition, view Blur Studio’s spectacularly remastered cutscenes from the original Halo 2 game. ![]()
![]() ![]() Having an address displayed clearly on the invoice allows sold products to have a return address and gives customers a means to pay invoices by check through the mail.Ī ‘Bill To’ section lists all of the significant details of the client purchasing the products or services. ![]() The company name can be replaced by an individual’s name if doing freelance work. The company name and address are staples of an invoice.
![]() ![]() ![]() The Trump administration will need to “bring back” a huge amount of manufacturing activity in the next few years if it is going to meaningfully address the plight of displaced production workers with new manufacturing jobs. How much of a manufacturing renaissance would be needed to repair the breach? Since 1980, the nation has lost some 6.4 million manufacturing jobs-more than one-third of the sector’s employment base. Restoring just half of those jobs in the next four years would require, factoring in current manufacturing efficiency and job sparseness, a massive 26 percent surge in manufacturing output. These bars report the steadily declining number of workers required to generate each $1 million of manufacturing output during the time period, given the sharply increased productivity of the sector.Īnd the story is dramatic: In 1980, it took 25 jobs to generate $1 million in manufacturing output in the U.S. Today, it takes just 6.5 jobs to generate that amount-and that’s after five more stable years of little change. But now look at the declining series of gray bars. Viewed positively, the diverging output and employment lines represent a success: They reflect solid increases in U.S. Here you can see in the two line plots that the inflation-adjusted output of the manufacturing sector is as high as it has ever been, while employment declined by more than 6 million jobs over 35 years. Take a look at this single, stark graph depicting the 35-year-history of U.S. Which is why we want to add this telling chart to the discussion about the future of manufacturing jobs. Nor will the difference be just a minor effect – it’s going to be major. The problem for Trump and blue-collar workers is that when manufacturing returns to the states (and several trends favor that), the associated job-creation will not be what it once was. ![]() ![]() While we aim to supply accurate product information, it is sourced by manufacturers, suppliers and marketplace sellers, and has not been provided by Overstock.
![]() As a result, pros can edit up to 30 streams of 4K ProRes video or up to seven streams of 8K ProRes video in Final Cut Pro - more streams than on a 28-core Mac Pro with Afterburner. ![]() 1 M1 Max also offers an enhanced media engine that features two ProRes accelerators for even higher multi-stream performance. 3D artists on the new MacBook Pro can now easily work with extreme geometry and textures in scenes that pro PC laptops can’t even run. With even the latest PC laptops topping out at 16GB of video memory, having this huge amount of memory available is game-changing for pro workloads, allowing pros to do things that were previously unimaginable on a notebook. It also has up to 400GB/s of memory bandwidth - 2x that of M1 Pro and nearly 6x that of M1 - and up to 64GB of fast unified memory. M1 Max features the same powerful 10-core CPU as M1 Pro, and doubles the GPU with up to a massive 32 cores for up to 4x faster GPU performance than M1. M1 Max - the world’s most powerful chip for a pro notebook - builds on M1 Pro, taking its amazing capabilities even further. Customers can order the new 14- and 16-inch MacBook Pro models today, and they will be available beginning Tuesday, October 26. ![]() The new MacBook Pro joins the 13-inch MacBook Pro with M1 to form the strongest lineup of pro notebooks ever. Shattering the limits of what a notebook can do, MacBook Pro is designed for developers, photographers, filmmakers, 3D artists, scientists, music producers, and anyone who wants the world’s best notebook. Combined with macOS Monterey, which is engineered down to its core to take full advantage of M1 Pro and M1 Max, the user experience is simply unrivaled. The new MacBook Pro also features a stunning Liquid Retina XDR display, a wide range of ports for advanced connectivity, a 1080p FaceTime HD camera, and the best audio system in a notebook. Available in 14- and 16-inch models, MacBook Pro delivers groundbreaking processing, graphics, and machine learning (ML) performance whether running on battery or plugged in, as well as amazing battery life - enabling workflows previously unimaginable on a notebook. I very recommend to check this video introduction Notice how perfect are diagrams and Data Editor.CUPERTINO, CALIFORNIA Apple today unveiled the completely reimagined MacBook Pro powered by the all-new M1 Pro and M1 Max - the first pro chips designed for the Mac. Because note again, they have own Valentina db engine and Valentina Server, as FileMaker and 4D. Guys say they will add forms in nearest months, then this will be FileMaker killer IMO :) We'll see. Diagrams can be used in free edition also.īut there is no forms as in Access. All this present in Valentina Studio for all that dbs. Was asked about relational support, 1:M, M:1, M:M links. I am using it up to now and so far all right. ![]() Perfect GUI for mySQL, PostgreSQL, SQLite and their own Valentina DB. It has totally free edition without limits. I have found this application in April of 2013. Since my first post was about Valentina Studio and I was asked to provide more info, here it is.
![]() Although Cytoscape has newer versions, jActiveModules and ClueGO plugins are verified to work in Cytoscape version 2.6.3.Įxternal tools: PANOGA utilizes four external web-servers to functionalize SNPs, i.e., SPOT, F-SNP, SNPnexus, SNPinfo jActiveModules plugin of Cytoscape to identify sub-networks ClueGO plugin 60 of Cytoscape 68 for functional enrichment of the identified sub-networks. Hence, to follow PANOGA protocol, users need to install Cytoscape version 2.6.3 by on a local computer by following the steps in Box 2 of the Cytoscape paper, published in Nature protocols. Subnetwork identification and functional enrichment steps of PANOGA protocol are realized by Cytoscape plugins. Each of these two Pw values combine functional information of a SNP and the genotypic p-value of a SNP, that is found to be significant in GWAS.Ĭytoscape: Cytoscape is an open source network data integration, analysis, and visualization platform. Sample_spot_fsnp_snpnexus.pvals: contains SPOT and F-SNP weighted p-values (Pw-values) for each SNP associated gene. This file illustrates the SIF, which offers a straightforward means to import networks into Cytoscape as text. HumanPPI.sif: contains a protein–protein interaction (PPI) network in a sif file format, as detailed in Figure 2. In addition to the sample GWAS data, several additional data files are available for readers wishing to follow this protocol as a tutorial: A sample PANOGA input file and SPOT, F-SNP, SNPnexus and SNPinfo input files are made available in PANOGA_protocol/data/ as sample_panoga_input.txt, sample_spot_input.txt, sample_fsnp_input.txt, sample_snpnexus_input.txt, sample_snpinfo_input.txt). As a result of the preprocessing step of PANOGA, four additional files in SPOT, F-SNP, SNPnexus and SNPinfo input file formats are created. genotypic p-values in a tab-delimited text file or excel file, as detailed in Figure 2. ( ).ĭata files: This protocol begins with a GWAS dataset containing SNP rsIDs vs. Java 2 platform: Standard Edition, version 5.0 or higher (Java SE 5 or higher). Hardware requirements: We recommend a 1 GHz CPU or higher, a high-end graphics card, 500MB of available hard disk space, at least 1 GB of free physical RAM and a minimum screen resolution of 1,024×768. EquipmentĪ computer with Windows or Linux OS and internet access. The pathways are ranked according to the significance scores and are referred as the SNP targeted pathways. Next, we find the KEGG pathways in these subnetworks and determine the significance of the modifications on these pathways. We then map these genes to a protein-protein interaction (PPI) network and determine the connected subnetworks targeted by the SNPs. To this end, our methodology starts with functionalization of several significant SNPs to identify effected genes. That’s why pathways have higher explanatory power towards understanding disease development mechanism. In this method, we hypothesize that these factors are crippling similar pathways in individuals. One possible reason of multifactorial diseases is the alterations in the activity of biological pathways. Since each factor would have modest effect on the disease development mechanism, it is challenging to identify significant individual factors. Multiple factors act on complex diseases. In this protocol, starting with a list of SNPs found to be associated with a disease in a GWAS, we propose a novel methodology to determine disease related (SNP targeted) pathways through the identification of SNP targeted genes within these pathways. genotypic p-values and is available at: Introduction The program accepts tab delimited or excel file containing SNP rsIDs vs. Additionally, PANOGA helps to identify other disease related genes, not targeted by the SNPs, which are also located within these affected pathways. We provide a protocol (termed PANOGA, Pathway and Network Oriented GWAS (Genome-wide association study) Analysis) to devise functionally important pathways through the identification of genes within these pathways, where these genes are targeted by single nucleotide polymorphisms (SNPs) obtained from the GWAS analysis. While each of these variations extends slightly the likelihood of having the disease, they work together to give birth to the perturbations in normal biological processes. One possible reason of multifactorial diseases is the alterations in the activity of biological pathways, where a series of mutations occur in distinct genes. The identification of the variants that explain familial risk of a specific disease is important since it enables the development of genetic risk prediction tests, diagnosis tools and therapeutical applications. Authors: Burcu Bakir-Gungor & Osman Ugur Sezerman ![]() ![]() Early withdrawal during this five-year period puts you at risk of additional tax penalties. The IRS requires you to convert your Roth IRA account at least five years before you plan to use it. Second, you’ll need to follow the five-year holding rule. A higher tax bracket can also affect the amount you pay for Medicare. Should this happen, you may end up owing more taxes on your Social Security benefits during retirement than you would accrue in savings. So, be sure that your Roth IRA conversion won’t increase your taxable income so much that you move into a higher tax bracket. Your beneficiaries can also generally withdraw funds from an inherited Roth IRA tax-free.įirst, the money you convert to a Roth IRA will generally be considered reportable income. Because Roth IRAs have no required minimum distributions, they can be a good way to allow your savings to continue to grow and be passed on to any beneficiaries. You might also choose a Roth IRA for estate planning purposes. Why might you opt for a Roth IRA conversion? If you expect to have a relatively high income during retirement, a conversion can reduce how much you’ll pay in taxes. ![]() In certain circumstances, it may benefit you to move some or all your money from one type of retirement account - such as a traditional, SIMPLE or SEP IRA or a qualified employer-sponsored retirement plan like a 401(k), 403(b) or 457(b) - into a Roth IRA. ![]() Also, Roth IRAs may be passed to a beneficiary on a tax-free basis, making them a good option for estate planning. Unlike many other retirement plans, Roth IRAs don’t have minimum distributions that you are required to withdraw from the account each year. Roth IRAs offer certain other advantages as well. So, withdrawals can be made tax- and penalty-free during retirement, provided the account holder is at least 59½ years of age and the account has been open for at least five years. But with a Roth IRA, you’ve already paid taxes on your contributions. Other retirement accounts, such as traditional IRAs and 401(k)s, are funded with pre-tax income, meaning contributions must be taxed at the time of withdrawal. Contributions to these accounts grow tax-free. What is a Roth IRA?Ī Roth IRA is a retirement savings account that’s funded with after-tax income. Learn about the most common Roth IRA conversion accounts and when they might be right for your situation. The right Roth IRA conversion strategy can help you minimize the taxes you’ll pay on your retirement savings while still allowing you to build wealth for the future. This is where a Roth IRA conversion may work well for you. As your circumstances change, it may make sense to pivot from one savings plan to another. Saving for retirement is a lifelong process, so it can be tricky to predict exactly which retirement accounts will be right for your situation. ![]() ![]() The right Roth IRA conversion strategy can help you minimize the taxes you’ll pay on your retirement savings while still allowing you to build wealth for the future.Roth IRA conversions can be a useful option if you expect to have a relatively high income during retirement, since a conversion can reduce how much you’ll pay in taxes.A Roth IRA conversion is when you roll some or all of the funds from other retirement accounts - such as traditional IRAs and 401(k)s - into a Roth IRA. ![]() |
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